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DNA vaccine protects against toxic proteins linked to Alzheimer's

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UT Southwestern researchers have developed a DNA vaccine that helps the physique shield in opposition to poisonous proteins related to Alzheimer’s illness. These photographs present amyloid plaque within the mouse mind utilizing plasma containing anti-amyloid antibody from massive mammals immunized with the vaccine. Credit score: Picture courtesy of UT Southwestern Medical Heart A brand new DNA vaccine when delivered to the pores and skin prompts an immune response that produces antibodies to guard in opposition to poisonous proteins related to Alzheimer's illness -- with out triggering extreme mind swelling that earlier antibody remedies brought on in some sufferers. Two research from the Peter O'Donnell Jr. Mind Institute show in animals how a vaccine containing DNA of the poisonous beta-amyloid protein elicits a unique immune response which may be protected for people. The vaccine, which can seemingly ...